Genomic integrity is constantly threatened by sources of DNA damage, internal and external alike.Among the most cytotoxic lesions is the DNA double-strand break (DSB) which arises from the cleavage of both strands of the double helix.Cells boast a peak thca vape considerable set of defences to both prevent and repair these breaks and drugs which de
The outcomes of relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) resistant to new drugs such as tyrosine kinase inhibitors, inotuzumab ozogamicin (InO) and blinatumomab are dismal.We treated two cases of Ph+ALL resistant to these drugs that achieved long-term survival after treatment with chimeric antigen receptor (CA
It is troubling that universities continue to have too few Aboriginal students, especially in social work, because of both the historical harm done through social work and the high percentage of Aboriginal clients in many areas of practice.This unseen sunscreen sale paper looks at ways post-secondary institutions can work towards reconciliation wit
Abstract Background Prolonged hospitalization leads to poorer health outcomes and consumes limited hospital resources.This study identified factors associated with prolonged length of stay (PLOS) among internal medicine patients admitted in a tertiary government hospital.Methods We reviewed the medical records of 386 adult patients admitted under t